Azacitidine

4 papers4 findings

1 lab in 1 country

Funders: Consejo Nacional de Ciencia y Tecnología and 1 more

Animals1
Model organisms1

Outcomes

4

Dengue virus infection

downin A. aegypti1

1 study

Azacitidine decreases dengue virus infection in A. aegypti (from 78% to 37%).
“reducing DENV2 infection prevalence from 78% to 37%”
Model organismsin heatwave-exposed mosquitoes
Dengue virus 2 vector competence in heatwave-exposed Aedes aegypti mosquitoes is reduced by 5-methylcytosine RNA disruption
Insect biochemistry and molecular biology25 Jul 2026

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Apoptosis

upin reviews1

1 study

Azacitidine induces apoptosis.
“extended/high-dose 5-azaC-mediated modulation can induce cell senescence or apoptotic/necrotic death”
Reviewextended or high-dose treatment
Can Molecular Attributes of Mammalian Granulosa Cells and Ovarian Putative Stem Cells Predestine Them to Be a Promising Tool for Tissue Engineering and Regenerative Medicine?
International journal of molecular sciences1 Nov 2025

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Cellular senescence

upin reviews1

1 study

Azacitidine induces cellular senescence.
“extended/high-dose 5-azaC-mediated modulation can induce cell senescence or apoptotic/necrotic death”
Reviewextended or high-dose treatment
Can Molecular Attributes of Mammalian Granulosa Cells and Ovarian Putative Stem Cells Predestine Them to Be a Promising Tool for Tissue Engineering and Regenerative Medicine?
International journal of molecular sciences1 Nov 2025

More on Cellular senescence

Lineage conversion

upin reviews1

1 study

Azacitidine induces lineage conversion.
“Recent advances in chemical modulation of epigenetic reprogramming, particularly with agents from the family of non-specific DNA methyltransferase (DNMT) inhibitors, such as 5-azacytidine (5-azaC), highlight the feasibility of generating functional, lineage-specific derivatives”
Reviewchemical modulationnon-specific DNA methyltransferase inhibitor
Can Molecular Attributes of Mammalian Granulosa Cells and Ovarian Putative Stem Cells Predestine Them to Be a Promising Tool for Tissue Engineering and Regenerative Medicine?
International journal of molecular sciences1 Nov 2025

Latest

5 in 12 months

Bulletin du Cancer19 h

Recommendations of the Groupe Francophone des Myélodysplasies (GFM) - Diagnostic approach and management of myelodysplastic syndromes, chronic myelomonocytic leukemias, and VEXAS syndrome

ReviewIndustry & policy

Frontiers in Medicine29 Aug

Therapy-related acute myeloid leukemia with 24-month latency after CD19 CAR-T cell therapy in relapsed/refractory diffuse large B-cell lymphoma: a case report

Case reportBlood and immune system

Insect Biochemistry and Molecular Biology26 Jul

Dengue virus 2 vector competence in heatwave-exposed Aedes aegypti mosquitoes is reduced by 5-methylcytosine RNA disruption

Experiments in model organismsMechanisms

NPJ Precision Oncology26 Apr

A machine learning-driven framework integrating cell death and senescence signatures for multi-target drug design and immunotherapy optimization in ovarian cancer

Experiments in miceOvarian cancer

International Journal of Molecular Sciences13 Nov

Can Molecular Attributes of Mammalian Granulosa Cells and Ovarian Putative Stem Cells Predestine Them to Be a Promising Tool for Tissue Engineering and Regenerative Medicine?

ReviewReproductive system

Archives of Toxicology13 Nov

Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells

Experiments in cellsInterventions

Cellular and Molecular Life Sciences30 Apr

Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes

Experiments in mouse cellsOxidative phosphorylation