CD8+ T cell activation

1 paper

Animals1

Latest

5 in 12 months

Cancer Research21 Sep

Senolytic Interventions Enhance the Anti-metastatic Activity of Chemotherapy in Prostate Cancer

Experiments in miceSenolytics

Nature Communications21 Sep

Sex-specific trajectories of nonlinear immune aging at single-cell level

Cohort study of 1,828 peopleImmune response

Cell Death & Disease6 May

Age-related differences and common pathways of lymphocyte subsets in sepsis: a comparative review of elderly and pediatric patients

ReviewMechanisms

NPJ Precision Oncology26 Apr

A machine learning-driven framework integrating cell death and senescence signatures for multi-target drug design and immunotherapy optimization in ovarian cancer

Experiments in miceOvarian cancer

Lab on a Chip9 Dec

Lymph node paracortex-inspired on-a-chip recapitulating immunosenescence: a cancer vaccine immunogenicity and antitumoral efficacy screening platform

Experiments in miceAI & data

Immunotherapy Advances29 Apr

Abnormal glucose and lipid metabolism promotes disrupted differentiation of T and B cell subsets in Behçet's disease

Study in peopleMechanisms

Nature Communications23 Jul

Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8⁺ T cell activation and limit responsiveness to immunotherapy in mice

Experiments in animalsInterventions

Journal of Hepatology10 Mar

Deregulated intracellular pathways define novel molecular targets for HBV-specific CD8 T cell reconstitution in chronic hepatitis B

Study in peopleInterventions