APELIN-12
- 1 lab in 1 country
- Funder: Henan Provincial People's Hospital
- Cells1
Outcomes
4SIRT6
upin human cells1
1 study
SIRT6
upin human cells1
APELIN-12 increases SIRT6 in human cells.
“Apelin-12 restored SIRT6 (but not SIRT1) expression”
Cellsin LPS-treated hDPCs
Molecular oral microbiology19 Oct 2025
Senescence-associated beta-galactosidase
downin human cells1
1 study
Senescence-associated beta-galactosidase
downin human cells1
APELIN-12 decreases senescence-associated beta-galactosidase in human cells.
“reducing senescence markers, including γH2AX and SA-β-Gal”
Cellsin LPS-treated hDPCs
Molecular oral microbiology19 Oct 2025
Telomerase activity
upin human cells1
1 study
Telomerase activity
upin human cells1
APELIN-12 increases telomerase activity in human cells.
“Apelin-12 treatment restored telomerase activity and upregulated human telomerase reverse transcriptase (hTERT)”
Cellsin LPS-treated hDPCs
Molecular oral microbiology19 Oct 2025
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
APELIN-12 decreases cellular senescence in human cells.
“Apelin-12 attenuates LPS-induced cellular senescence in hDPCs via SIRT6-mediated pathways”
Cellsin LPS-treated hDPCs
Molecular oral microbiology19 Oct 2025
Latest
Molecular Oral Microbiology
Apelin-12 Attenuates LPS-Induced Cellular Senescence in Human Dental Pulp Cells via SIRT6-Mediated Pathways: Implications for Gingivitis Management
Experiments in human cellsInterventions