Angiotensin 1-7
Angiotensin 1-7 has been studied in 2 papers since 2018: none in people yet, 2 in animals. The research so far is in animals. The newest paper, May 14, 2024: “Combining experiments and bioinformatics to identify transforming growth factor-β1 as a key regulator in angiotensin II-induced trophoblast senescence”.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Japan Society for the Promotion of Science and 2 more
- Animals2
What did studies of Angiotensin 1-7 find?
2Studies of Angiotensin 1-7 measured 2 outcomes; the most studied are p16INK4a expression (1 study) and grip strength (1).
p16INK4a expression
no changein mice1
1 study
p16INK4a expression
no changein mice1
Angiotensin 1-7 has no effect on p16INK4a expression in mice.
“Angiotensin 1-7 did not alter the expression of p16INK4a or central nuclei in TA muscles of both types of mice.”
AnimalsWild-type and ACE2KO micetibialis anterior muscle4 weeksmales
Journal of cachexia, sarcopenia and muscle
Grip strength
upin mice1
1 study
Grip strength
upin mice1
Angiotensin 1-7 improves grip strength in mice (+3.8 ± 1.5% in wild-type and +13.3 ± 3.1% in ACE2KO mice).
“Angiotensin 1-7 improved grip strength in both types of older mice, with larger effects observed in ACE2KO mice”
AnimalsWild-type and ACE2KO mice4 weeksmales
Journal of cachexia, sarcopenia and muscle
Funding
2 grants since 2019National Heart, Lung, and Blood InstituteUS$106kNational Institute on AgingUS$50k