p16INK4a expression

Biomarker

3 papers1 finding

  • Humans1
  • Animals2

Interventions

1

Smoking

upin humans1

1 study
  1. Smoking increases p16INK4a expression in humans.

    “p16(INK4a) expression did not independently correlate with gender or body-mass index, but was significantly associated with tobacco use and physical inactivity.”

    Humansperipheral blood T-lymphocytes

    Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging

    Aging cell22 May 2009

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Aging

Tiny vesicles spread senescence in lab-grown human cells

In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.In lab-grown human fibroblasts, tiny vesicles from senescent cells prompted dividing cells to halt division and activate a DNA damage response.

Experiments in human cellsCellular senescence