2-deoxyglucose
- 1 lab in 1 country
- Animals2
Outcomes
1Lifespan
upin rats1
1 study
Lifespan
upin rats1
2-deoxyglucose extends lifespan in rats.
“chronic peripheral injection of 2 deoxy-d-glucose promotes hypothalamic AMP-activated protein kinase (AMPK) activation, increases food intake, and prolongs the survival of anorexic tumor-bearing (TB) rats.”
Animalsin anorexic tumor-bearing ratshypothalamus
Endocrinology23 Aug 2007
Latest
Acta Odontologica Scandinavica
Advanced glycation end products induce inflammaging in periodontal ligament fibroblasts through RAGE/AKT/mTOR/glycolysis pathway
Experiments in human cellsmTOR signalling
ADA Scientific Sessions 2025 Abstract
Region-Specific Effects of Early Aging on Glucose Metabolism in the Brain
Experiments in 9 miceMechanisms
Cell Death & Disease
Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling
Experiments in miceFOXO signalling
Nature Communications
D-Glucosamine supplementation extends life span of nematodes and of ageing mice
Experiments in wormsInterventions
Endocrinology
A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia
Experiments in ratsInterventions
Annals of the New York Academy of Sciences
Caloric restriction mimetics: the next phase
ReviewDietary restriction
Annals of the New York Academy of Sciences
Development of calorie restriction mimetics as a prolongevity strategy
ReviewDietary restriction
Annals of the New York Academy of Sciences
Caloric restriction in primates and relevance to humans
Experiments in non-human primatesDietary restriction
Journal of Neuroscience Research
Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism
Experiments in ratsDietary restriction