SOGA1

1. SOGA1 decreases nonalcoholic steatohepatitis in mice.

   “lentiviral vectors of sh-SOGA1 were injected into NASH mice and found that SOGA1 knockout alleviated NASH progression in mice.”

   Animalsin NASH mice

   Knockdown of suppressor of glucose by autophagy (SOGA1) alleviates the progression of non-alcoholic steatohepatitis (NASH) by reducing hepatocyte senescence through regulating AMPK/mTOR-mediated mitochondrial homeostasis

   BMC biotechnology·23 May 2026

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