SLC39A14
GeneHomo sapiens1 paper1 findingHGNC 20858NCBI Gene 23516Taxon 9606
- Cells1
Effects
1Zinc
is required forin animals1
1 study
Zinc
is required forin animals1
SLC39A14 is required for zinc.
“In vivo experiments verified that ZIP14 (SLC39A14) is required to maintain intracellular Zn 2 + levels and sustain ANXA2-mTOR signaling.”
Animalsmaintaining intracellular levels
Zinc influx promotes mitophagy to slow intervertebral disc degeneration · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1CellsMitochondria
Zinc influx promotes mitophagy to slow intervertebral disc degeneration
Targeting the zinc transporter ZIP14 and ANXA2 deacetylation restores autophagic flux and limits degenerative spinal disease in experimental models.