PPP2CB

1 paper1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: National Institutes of Health

Cells1

Effects

1

Cellular senescence

upin human cells1

1 study

PPP2CB increases cellular senescence in human cells.
“Knockdown of PPP2CB using siRNA phenocopies the effects of miR-425 overexpression, reducing senescence, enhancing proliferative potential, and increasing RB phosphorylation.”
Cellsshown by siRNA knockdown
miR-425-5p Regulates Cellular Senescence Through Modulation of Retinoblastoma Protein Phosphorylation
bioRxiv (Cold Spring Harbor Laboratory)19 Jun 2026Preprint

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bioRxiv19 Jun

miR-425-5p Regulates Cellular Senescence Through Modulation of Retinoblastoma Protein Phosphorylation

Preprint: experiments in human cellsCell cycle regulation