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PEG3

Gene

3 papers2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1
  • In silico1

Effects

1

Cellular senescence

upin mouse cells1

1 study

  1. PEG3 increases cellular senescence in mouse cells.

    “Peg3, a novel target of TZ, mediates inflammation-induced VSMC apoptosis and senescence.”

    CellsAng II-induced VSMCs, shown by knockdown

    Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence

    European journal of pharmacology7 Feb 2024

More on Cellular senescence

Associations

1

MIR1931

mixedin silico1

1 study

  1. PEG3 is associated with MIR1931 in silico.

    “Gene-miRNA coregulatory network found that Peg3 and mmu-miR-1931 in DEGs were related to each other”

    In silicogene-miRNA coregulatory network analysis

    Differential gene screening and bioinformatics analysis of epidermal stem cells and dermal fibrblasts during skin aging

    Research Square18 Apr 2022Preprint

More on MIR1931

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