NSD1

2 papers study it1 finding

1 lab in 1 country

Funders: Chinese Academy of Sciences and 2 more

Animals2

Effects

1

chondrogenesis

is required forin mice1

1 study

NSD1 is required for chondrogenesis in mice.
“Immunostaining results showed decreased anabolic and increased catabolic activities in Nsd1Prrx1-Cre mice, along with decreased chondrogenic differentiation.”
AnimalsNsd1 conditional knockout (Nsd1Prrx1-Cre mice)
H3K36 methyltransferase NSD1 protects against osteoarthritis through regulating chondrocyte differentiation and cartilage homeostasis
Cell death and differentiationNov 27, 2023

Latest

Cell Death DiscoveryMay 9

Macrophage-derived ectosomal miR-350-3p promotes osteoarthritis progression through downregulating chondrocyte H3K36 methyltransferase NSD1

Experiments in miceBones and joints

Cell Death and DifferentiationNov 28

H3K36 methyltransferase NSD1 protects against osteoarthritis through regulating chondrocyte differentiation and cartilage homeostasis

Experiments in miceCellular homeostasis