NPM1
GeneHomo sapiens1 paper1 findingHGNC 7910NCBI Gene 4869Taxon 9606
- Cells1
Effects
1Epigenetic alterations
is required forin human cells1
1 study
Epigenetic alterations
is required forin human cells1
NPM1 is required for epigenetic alterations in human cells.
Cellsfor nucleolar buffering and heterochromatin maintenance under Progerin stress
Nucleoli buffer displaced heterochromatin to limit premature aging programs in cells · bioRxiv · 1 Oct 2026 · Preprint
Latest
1CellsPreprint
Nucleoli buffer displaced heterochromatin to limit premature aging programs in cells
In cells expressing progerin, the nucleolus sequesters released lamina-associated domains to preserve gene repression and prevent worsening DNA damage.