NLRP1

Gene

2 papers1 finding

HGNCNCBI GeneTaxon

  • 1 lab in 1 country
  • Funders: Agencia Estatal de Investigación and 4 more
  • Animals2

Effects

1

Inflammation

upin mice1

1 study
  1. NLRP1 increases inflammation in mice.

    “by 16 months of age, Nlrp3 heterozygous mice exhibited signs of accelerated inflammatory aging, driven by compensatory overexpression of NLRP1.”

    Animalsin Nlrp3 heterozygous mice

    NLRP3 haploinsufficiency unmasks a compensatory NLRP1-NLRP3 interaction that drives accelerated aging in mice

    Science advances26 Jun 2026

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