MYO1C

Gene1 paper3 findingsHGNC 7597NCBI Gene 4641Taxon 9606

  • Animals1

Effects

3

Scotopic dysfunction

downin mice1

1 study
  1. MYO1C protects against scotopic dysfunction in mice.

    Animalsrod-specific deletion

    Loss of MYO1C causes age-dependent rod dysfunction in mice · bioRxiv : the preprint server for biology · 9 Sep 2026 · Preprint

rhodopsin trafficking

is required forin human cells1

1 study
  1. MYO1C is required for rhodopsin trafficking in human cells.

    Cellsdeletion of MYO1C C-terminal domain

    Loss of MYO1C causes age-dependent rod dysfunction in mice · bioRxiv : the preprint server for biology · 9 Sep 2026 · Preprint

Retinal dysfunction

downin mice1

1 study
  1. MYO1C protects against retinal dysfunction in mice.

    Animalsknockout

    Loss of MYO1C causes age-dependent rod dysfunction in mice · bioRxiv : the preprint server for biology · 9 Sep 2026 · Preprint

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bioRxivAnimalsPreprint

Loss of MYO1C causes age-dependent rod dysfunction in mice

Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.