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MIR6779

Gene

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 3 more
  • Cells1

Effects

3

XIAP

downin human cells1

1 study

  1. MIR6779 inhibits XIAP in human cells.

    “miR-6779 targeted inhibition of X-linked inhibitor of apoptosis protein (XIAP) expression.”

    Cellsin IL-1β-treated chondrocytes

    The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis

    Animal models and experimental medicine4 Feb 2025

More on XIAP

Apoptosis

upin human cells1

1 study

  1. MIR6779 activates apoptosis in human cells.

    “miR-6779 overexpression remarkably attenuated IL-1β effects on chondrocytes by reducing MMP3 and MMP13 levels, promoting cell apoptosis, suppressing cell senescence”

    Cellsin IL-1β-treated chondrocytes

    The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis

    Animal models and experimental medicine4 Feb 2025

More on Apoptosis

Cellular senescence

downin human cells1

1 study

  1. MIR6779 inhibits cellular senescence in human cells.

    “miR-6779 overexpression remarkably attenuated IL-1β effects on chondrocytes by reducing MMP3 and MMP13 levels, promoting cell apoptosis, suppressing cell senescence”

    Cellsin IL-1β-treated chondrocytes

    The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis

    Animal models and experimental medicine4 Feb 2025

More on Cellular senescence

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