There are 5 papers on Lsd-2 in aging research: none in people yet, 5 in animals.
At a glance
The findings reach worms or flies, none yet in people. 2 independent labs in 2 countries.
None of its findings points the other way.
Worms or flies: a single group. Cells, mice and humans: nothing yet.
- 2 independent labs in 2 countries
- Funders: Ministry of Science and Technology of the People's Republic of China and 5 more
- Model organisms5
Interventions
1Gomisin N
upin flies1
1 study
Gomisin N
upin flies1
Gomisin N increases Lsd-2 in high-fat diet groups.
“induced a specific upregulation of lipid storage droplet (Lsd)-2”
Model organismsin high-fat diet groups
Functional Characterization of Gomisin N in High-Fat-Induced Drosophila Obesity Models
International journal of molecular sciences
Upstream
1Ugt35b
upin flies1
1 study
Ugt35b
upin flies1
Ugt35b increases Lsd-2 in flies (knockdown in glia).
“downregulating Lsd-2 expression”
Model organismsknockdown in gliabrain
Cell reports
Latest
Biogerontology
Dissecting metabolic regulation of behaviors and physiology during aging in Drosophila
Experiments in fliesMethionine and one-carbon metabolism
Research Square
Dissecting Metabolic Control of Behaviors and Physiology During Aging in Drosophila
Preprint: experiments in fliesLipid and ceramide metabolism
Cell Reports
The glial UDP-glycosyltransferase Ugt35b regulates longevity by maintaining lipid homeostasis in Drosophila
Experiments in fliesMechanisms
International Journal of Molecular Sciences
Functional Characterization of Gomisin N in High-Fat-Induced Drosophila Obesity Models
Experiments in fliesObesity
Developmental Cell
HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila
Experiments in fliesProteostasis