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GLIS1

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 1 more
  • Humans1

Effects

1

Cellular senescence

downin human cells1

1 study

  1. GLIS1 decreases cellular senescence in human cells.

    “The downregulation of GLIS1 induced cell senescence and renal fibrosis by shifting metabolic remodeling from fatty acid oxidation (FAO) to glycolysis.”

    Cellsshown by GLIS1 downregulation

    N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1

    BMC biology31 Dec 2024

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