GJA1

  • 2 independent labs in 2 countries
  • 1 trial
  • Funders: Agencia Estatal de Investigación and 6 more
  • 1 of 1 trial sponsored by developers of drugs on it
  • Animals2
  • Cells1

Effects

1

Mechanotransduction

mediatesin mice1

1 study
  1. GJA1 mediates mechanotransduction in mice.

    Animalsdownstream of Yoda1-induced Piezo1 activationosteocytemales

    Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

    Aging cell22 Aug 2026

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Associations

3

Senescence-associated beta-galactosidase

upin human cells1

1 study
  1. GJA1 is associated with senescence-associated beta-galactosidase in human cells.

    Cellsintervertebral disc

    A novel target associated with senescence and inflammatory signaling in human intervertebral disc degeneration

    bioRxiv3 Sep 2026Preprint

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TP53

upin human cells1

1 study
  1. GJA1 is associated with TP53 in human cells.

    Cellsintervertebral disc

    A novel target associated with senescence and inflammatory signaling in human intervertebral disc degeneration

    bioRxiv3 Sep 2026Preprint

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Intervertebral disc degeneration

upin human cells1

1 study
  1. GJA1 is associated with intervertebral disc degeneration in human cells.

    Cellsintervertebral disc

    A novel target associated with senescence and inflammatory signaling in human intervertebral disc degeneration

    bioRxiv3 Sep 2026Preprint

More on Intervertebral disc degeneration

Latest

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