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FABP

Gene

2 papers study it3 findings

NCBI GeneTaxon

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Inha University and 7 more
  • Model organisms2

Effects

3

Autophagy

upin flies1

1 study

  1. FABP activates autophagy in flies.

    “fabp overexpression stimulated autophagy”

    Model organisms

    Neuronal fatty acid-binding protein enhances autophagy and suppresses amyloid-β pathology in a Drosophila model of Alzheimer's disease

    PLoS genetics

More on Autophagy

Alzheimer's disease

downin flies1

1 study

  1. FABP protects against Alzheimer's disease in flies.

    “fabp overexpression ameliorated Aβ pathology.”

    Model organismsin an AD modelneurons

    Neuronal fatty acid-binding protein enhances autophagy and suppresses amyloid-β pathology in a Drosophila model of Alzheimer's disease

    PLoS genetics

More on Alzheimer's disease

Lifespan

downin flies1

1 study

  1. FABP shortens lifespan in flies.

    “Neuronal knockdown of fabp shortened the lifespan of flies”

    Model organismsneuronal knockdownbrain

    Neuronal fatty acid-binding protein enhances autophagy and suppresses amyloid-β pathology in a Drosophila model of Alzheimer's disease

    PLoS genetics

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