E2F2

1. E2F2 increases stem cell differentiation in human cells.

   “while it suppressed mineralization, ALP activity, and the expression of osteogenesis-associated markers (BMP2, OCN, OPN, Runx2, Osterix) in yDPSCs.”

   Cellsin young dental pulp stem cells

   E2F2 suppresses cell senescence and promotes odontogenic differentiation in dental pulp stem cells by stabilizing METTL3

   Odontology·20 Mar 2026

More on Stem cell differentiation

1. E2F2 decreases cellular senescence in human cells.

   “Knockdown of E2F2 increased the proportion of SA-β-gal-positive cells and upregulated the senescence markers p21 and p16”

   Cellsin young dental pulp stem cells

   E2F2 suppresses cell senescence and promotes odontogenic differentiation in dental pulp stem cells by stabilizing METTL3

   Odontology·20 Mar 2026

More on Cellular senescence

1. Sepsis-induced acute respiratory distress syndrome increases E2F2 in mice.

   “E2f2, Ezh2, and Ube2c genes had a higher expression in the sepsis-induced ALI/ARDS subgroup than in the control subgroup”

   Animalsin sepsis-induced ALI/ARDS mouse model

   Machine learning methods identified cellular senescence-related hub molecules in sepsis-induced acute respiratory distress syndrome (ARDS) and their upstream regulatory network

   Molecular biology reports·6 Jun 2026

More on Sepsis-induced acute respiratory distress syndrome