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Tissue & CellReview·28 Aug

Estrogen signaling and ferroptosis in intervertebral disc degeneration: A proposed mechanistic framework and its evidence gaps

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Extracellular matrix remodelling1
Ferroptosis1
GPER11
Lipid and ceramide metabolism1
NF-κB signalling1
Oxidative stress and ROS signalling1
Sex hormone signalling (oestrogen, androgen)1
Estradiol1
Estrogen replacement therapy1
Intervertebral disc degeneration1
Raloxifene1

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