CARNS1

4 papers2 findings

HGNC NCBI Gene Taxon

2 independent labs in 2 countries

Funders: Centre Scientifique et Technique du Bâtiment and 8 more

Humans2
Animals2

Effects

1

Hematopoietic injury

is required forin mice1

1 study

CARNS1 is required for hematopoietic injury in mice.
“these effects were largely abrogated by specific deletion of carnosine synthase Carns1 in skeletal muscles”
Animalsin skeletal muscles of exercised mice after ionizing radiation
Exercise alleviates hematopoietic stem cell injury following radiation via the carnosine/Slc15a2-p53 axis
Cell communication and signaling : CCSDec 3, 2024

Upstream

1

Parkinson's disease

downin humans1

1 study

Parkinson's disease decreases CARNS1 in humans.
“identify genes lost over the aging and disease process, including CARNS1”
Humansmidbrain
A single-nuclei paired multiomic analysis of the human midbrain reveals age- and Parkinson's disease-associated glial changes
Nature agingMar 15, 2024

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