ATG5
GeneHomo sapiens1 paper1 findingHGNC 589NCBI Gene 9474Taxon 9606
- Animals1
Effects
1Autophagy
is required forin human cells1
1 study
Autophagy
is required forin human cells1
ATG5 is required for autophagy in human cells.
Cellsupon nutrient restriction, via Cys19 oxidation
Dietary restriction activates autophagy through selective oxidation of ATG5 · bioRxiv : the preprint server for biology · 24 Sep 2026 · Preprint
Latest
1Dietary restriction activates autophagy through selective oxidation of ATG5
Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation in mice.