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ahr-1

Gene

4 papers1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Research Foundation and 1 more
  • Animals1
  • Model organisms3

Effects

1

Gut barrier integrity

is required forin worms1

1 study

  1. ahr-1 is required for gut barrier integrity in worms.

    “These findings establish AHR as a critical mediator of fasting-induced intestinal resilience, revealing a previously unrecognized regulatory axis linking metabolic sensing to gut barrier homeostasis.”

    Model organismsrequired for fasting-induced protection; shown using AHR-deficient strains CZ2485 and ZG24intestine

    Aryl Hydrocarbon Receptor Is Required for Fasting-Induced Improvement of Gut Barrier Integrity in Caenorhabditis elegans

    Antioxidants (Basel, Switzerland)24 Jul 2025

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