Small airway fibrosis

1. SCGB1A1 decreases small airway fibrosis in mice.

   “Unchallenged Cc16-/- mice developed greater increases in lung compliance, airspace enlargement, and small airway fibrosis than age-matched WT mice over 6-18 months of age.”

   Animalsshown by Cc16 knockout versus age-matched wild-type micesmall airway

   Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice

   Physiological reports·Aug 1, 2018

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