Papers on skeletal muscle pathologies

21 papers

Thursday, August 27

AntioxidantsAug 27

Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle

RNAi-mediated silencing of pdr-1 and lgg-1 mitigates age-related mitochondrial fragmentation and promotes nuclear degradation in C. elegans muscle cells.

Experiments in wormsMitochondrion

Paper

Sunday, May 3

Skeletal MuscleMay 3

Senescence dynamics define therapeutic windows for Duchenne muscular dystrophy in DBA/2-mdx mice

Experiments in miceInterventions

Paper

Tuesday, December 2

Biochemical PharmacologyDec 2

Dual role of macrophages in skeletal muscle atrophy: Mechanisms and therapeutic strategies

ReviewMuscle

Paper

Tuesday, October 28

CellsOct 28

Immunoproteasomes in Skeletal Muscle Pathologies: Emerging Roles, Conflicting Evidence, and Future Directions

ReviewMuscle

Paper

Wednesday, November 13

NutrientsNov 13

Body Composition and Senescence: Impact of Polyphenols on Aging-Associated Events

ReviewPolyphenols

Paper

Thursday, October 31

Cell Death DiscoveryOct 31

Lipids associated with autophagy: mechanisms and therapeutic targets

ReviewMechanisms

Paper

Tuesday, September 10

Schizophrenia ResearchSep 10

The neuromuscular basis of functional impairment in schizophrenia: A scoping review

ReviewMechanisms

Paper

Thursday, March 21

JACC Basic to Translational ScienceMar 21

Caloric Restriction Rejuvenates Skeletal Muscle Growth in Heart Failure With Preserved Ejection Fraction

Experiments in ratsDietary restriction

Paper

Wednesday, December 6

JCI InsightDec 6

Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia

Experiments in animalsCachexia

Paper

Friday, April 14

NutrientsApr 14

Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota

ReviewNeurodegenerative disease

Paper

Tuesday, December 13

Molecular MetabolismDec 13

p21 induces a senescence program and skeletal muscle dysfunction

Experiments in miceOxidative phosphorylation

Paper

Saturday, December 25

Frontiers in PhysiologyDec 25

Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function

Experiments in animalsMuscle

Paper

Sunday, November 14

Skeletal MuscleNov 14

The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies

ReviewEndoplasmic reticulum

Paper

Friday, January 8

Journal of Applied PhysiologyJan 8

Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis

Experiments in miceExercise

Paper

Thursday, October 1

International Journal of Molecular SciencesOct 1

PAI-1, the Plasminogen System, and Skeletal Muscle

ReviewMechanisms

Paper

Thursday, March 28

BoneMar 28

Aging of the musculoskeletal system: How the loss of estrogen impacts muscle strength

ReviewMuscle

Paper

Monday, October 8

Arthritis Care & ResearchOct 8

Chronic Inflammation in Rheumatoid Arthritis and Mediators of Skeletal Muscle Pathology and Physical Impairment: A Review

ReviewMechanisms

Paper

Tuesday, May 8

Cell DiscoveryMay 8

Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins

Experiments in miceMuscle

Paper

Saturday, March 4

Progress in Molecular Biology and Translational ScienceMar 4

Mitochondrial-Targeted Catalase: Extended Longevity and the Roles in Various Disease Models

ReviewInterventions

Paper

Wednesday, December 28

AgingDec 28

Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging

Experiments in animalsTP53

Paper

Sunday, July 2

Nature MedicineJul 2

rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice

Experiments in miceMuscle

Paper