There are 10 papers on severe hypertriglyceridemia in aging research: 1 trial and 2 observational studies in people, 5 reviews.
10 papers study it9 more mention it1 finding
7 new papers in 30 daysSee all 19 papers on severe hypertriglyceridemia
“severe HTG, and diabetes with an odds ratios (95% confidence intervals) of 1.289 (1.002-1.658), 1.438 (1.076-1.921), and 1.384 (1.022-1.875)”
- Human trial1
- Humans2
Associations
1KSR2
upin humans1OR 1.438
1 study
KSR2
upin humans1OR 1.438
KSR2 is linked with a higher risk of severe hypertriglyceridemia in humans (OR 1.438, 95% CI 1.076-1.921).
“severe HTG, and diabetes with an odds ratios (95% confidence intervals) of 1.289 (1.002-1.658), 1.438 (1.076-1.921), and 1.384 (1.022-1.875)”
Humansn = 1,788
Genetic testing and molecular biomarkers
Trial sponsors
Company5 trialsPhase 32,174 people
Company2 trialsPhase 31,022 people
Company2 trialsPhase 3858 people
Company2 trialsPhase 3757 people
Company1 trialPhase 260 people
Company1 trialPhase 252 people
Latest
13 papers in 12 monthsFrontiers in Cardiovascular Medicine
Paracentral acute maculopathy (PAMM) associated with severe hypertriglyceridemia: a case report with a new therapeutic approach
Accepted, not yet published: case reportSevere hypertriglyceridemia
Current Atherosclerosis Reports
Targeting Apolipoprotein C-III in Hypertriglyceridemia: Implications for Pancreatitis and Cardiovascular risk
ESC Congress 2026 Abstract
Long-term efficacy and safety of olezarsen in patients with severe hypertriglyceridemia
Cohort study of 884 peopleSevere hypertriglyceridemia
ESC Congress 2026 Abstract
Dose-related effects of olezarsen in hypertriglyceridaemia: a systematic review and meta-analysis of 2,610 patients
Meta-analysis of randomized trialsHypertriglyceridemia
Clinica Chimica Acta; International Journal of Clinical Chemistry
Clinical utility of the lipemic index for identifying severe triglyceride-rich lipoprotein disorders in adults undergoing routine blood testing
Cross-sectional study of 71,768 peopleTriglyceride
Journal of Cardiovascular Pharmacology
Silencing Triglycerides: The Clinical Impact of Plozasiran and apoC-III Inhibition in Severe Hypertriglyceridemia
Genetic Testing and Molecular Biomarkers
The KSR2-rs7973260 Polymorphism is Associated with Metabolic Phenotypes, but Not Psychological Phenotypes, in Chinese Elders
Cohort study of 1,788 peopleMetabolic syndrome