Persistent prediabetes
Disease1 paper2 findings
- Human trial1
Associations
2Ceramide C18:0/C18:1 ratio
upin humans1OR 1.85
1 study
Ceramide C18:0/C18:1 ratio
upin humans1OR 1.85
Ceramide C18:0/C18:1 ratio raises the risk of persistent prediabetes in humans (OR 1.850, 95% CI 1.047-3.271 per 1-SD).
Humansadjusted for age, sex, race, adiposity, insulin sensitivity and secretion, and percentage changes in weight and waist circumference5 years
Baseline Plasma Metabolites Associated with Subsequent Response to Lifestyle Intervention in People with Prediabetes · The Journal of clinical endocrinology and metabolism · 1 Oct 2026
2-hour plasma glucose
upin humans1OR 2.405
1 study
2-hour plasma glucose
upin humans1OR 2.405
2-hour plasma glucose raises the risk of persistent prediabetes in humans (OR 2.405, 95% CI 1.341-4.312 per 1-SD).
Humansadjusted for age, sex, race, adiposity, insulin sensitivity and secretion, and percentage changes in weight and waist circumference5 years
Baseline Plasma Metabolites Associated with Subsequent Response to Lifestyle Intervention in People with Prediabetes · The Journal of clinical endocrinology and metabolism · 1 Oct 2026