Pancreatic ductal adenocarcinoma
Disease2 papers3 findings
- Humans2
Effects
1Subcutaneous fat index
downin humans1
1 study
Subcutaneous fat index
downin humans1
Pancreatic ductal adenocarcinoma decreases subcutaneous fat index in humans (-0.53 cm2/m2/month).
Humansprior to PDAC diagnosis vs matched controls
Longitudinal body composition changes distinguish pancreatic ductal adenocarcinoma from controls in a pre-diagnostic CT cohort · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 25 Sep 2026
Associations
2Skeletal muscle index
upin humans1
1 study
Skeletal muscle index
upin humans1
Skeletal muscle index predicts pancreatic ductal adenocarcinoma in humans (AUC 0.76 (95% CI, 0.73-0.78)).
Humanslongitudinal changes closer to diagnosis
Longitudinal body composition changes distinguish pancreatic ductal adenocarcinoma from controls in a pre-diagnostic CT cohort · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 25 Sep 2026
Pancreatic volume decline
upin humans1
1 study
Pancreatic volume decline
upin humans1
Pancreatic ductal adenocarcinoma is associated with pancreatic volume decline in humans (9.71 vs. 1.23 mL).
“PDAC patients showed more rapid PV decline than matched controls (5-year reduction 9.71 vs. 1.23 mL; p = 0.013)”
Humanspre-diagnostic CT imaging ≥5 years pre-index5 years
Accelerated Pancreatic Volume Loss as a Potential Pre-Diagnostic Imaging Biomarker for Pancreatic Cancer Risk Enrichment: An AI-Assisted Volumetric Study · Cancers · 21 Sep 2026