iScience
RAS/MAPK overactivation drives motor axon loss in flies
An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues in a dose-dependent…An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues in a dose-dependent manner.
Experiments in fliesMAPK/ERK signalling