MDPL syndrome
1 paper5 findings
- Cells1
Associations
5Mitochondrial reactive oxygen species
upin human cells1
1 study
Mitochondrial reactive oxygen species
upin human cells1
MDPL syndrome is associated with mitochondrial reactive oxygen species in human cells.
“(v) increased levels of mitochondrial reactive oxygen species (ROS)”
CellsMDPL syndromehiPSC-derived mesenchymal stem cellsn = 3
Aging26 Nov 2024
Telomere length
downin human cells1
1 study
Telomere length
downin human cells1
MDPL syndrome is associated with telomere length in human cells.
“(iv) reduced telomere length”
CellsMDPL syndromehiPSC-derived mesenchymal stem cellsn = 3
Aging26 Nov 2024
Cell-cycle progression
downin human cells1
1 study
Cell-cycle progression
downin human cells1
MDPL syndrome is associated with cell-cycle progression in human cells.
“(iii) slow cell proliferation and cell cycle progression”
CellsMDPL syndromehiPSC-derived mesenchymal stem cellsn = 3
Aging26 Nov 2024
Cell proliferation
downin human cells1
1 study
Cell proliferation
downin human cells1
MDPL syndrome is associated with cell proliferation in human cells.
“(iii) slow cell proliferation and cell cycle progression”
CellsMDPL syndromehiPSC-derived mesenchymal stem cellsn = 3
Aging26 Nov 2024
Nuclear morphology abnormalities
upin human cells1
1 study
Nuclear morphology abnormalities
upin human cells1
MDPL syndrome is associated with nuclear morphology abnormalities in human cells.
“we detected several hallmarks of senescence, including (i) abnormal nuclear morphology, (ii) micronuclei presence”
CellsMDPL syndromehiPSC-derived mesenchymal stem cellsn = 3
Aging26 Nov 2024