Marfan syndrome
- Humans1
- Animals5
Trial sponsors
1 trialPhase 3608 people
Assistance Publique - Hôpitaux de Paris
1 trialPhase 3303 people
Fondazione IRCCS Policlinico San Matteo di Pavia
1 trialPhase 3291 people
1 trialPhase 340 people
1 trialPhase 322 people
University of British Columbia
1 trialPhase 217 people
Latest
2 in 12 monthsAmerican Journal of Physiology Heart and Circulatory Physiology
Growth arrest of thoracic aortic aneurysms in aging Marfan mice
Experiments in miceMechanisms
AHA Scientific Sessions 2025 Abstract
Indexed baseline ascending aortic size shows non-linear relationship with future growth rate.
Cohort study of 3,349 peopleBiomarkers
bioRxiv
Growth Arrest of Thoracic Aortic Aneurysms in Aging Marfan Mice
Preprint: experiments in miceMechanisms
Journal of the American Heart Association
Endothelial Cell Senescence in Marfan Syndrome: Pathogenesis and Therapeutic Potential of TGF-β Pathway Inhibition
Experiments in cellsMechanisms
Biochemical Pharmacology
Stabilisation of extracellular matrix is crucial to rapamycin-mediated life span increase in Marfan mgR/mgR mice
Experiments in miceRapamycin
Frontiers in Physiology
Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model
Experiments in animalsMechanisms
Aging and Disease
Loss of Cisd2 Exacerbates the Progression of Age-Related Hearing Loss
Experiments in animalsMechanisms