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  • NCT00627393

    Phase 3Completed2008114 people3 Mar 2008clinicaltrials.gov

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    Direct AMPK activation modestly lengthens lifespan in short-lived species

    ResearchFight Aging!

    Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

    ResearchNature Aging and 1 more

    Senescence-inhibiting isoform Δ133p53α slows premature aging in mice

    Researchnpj Aging

    Figure 1

    Trials

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    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered1 Oct 2026

    Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes

    Institut de Recherches Cliniques de Montreal

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    Evidence →
    1. Intervention · 64 papersExercise
    2. Gene · 21 papersAPOE
    3. Disease · 122 papersCardiovascular disease
    4. Process · 116 papersInflammation
    5. Biomarker · 43 papersBody mass index
    6. Intervention · 42 papersGLP-1 receptor agonists

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    • Mechanisms278
    • Interventions391
    • Biomarkers371
    • Populations541
    • AI & data141
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