Investigative Ophthalmology & Visual Science
Aging is linked to immune shifts in mouse tear glands
An analysis of 47,537 cells from young and old male mice linked aging to altered immune balance in tear-producing glands.An analysis of 47,537 cells from young and old male mice linked aging to altered immune balance in tear-producing glands.
Mouse studyImmune response
Who was studiedYoung and aged male C57BL/6J mice, against young male mice
What changedOlder mice had greater representation of T cells, B cells, and plasma cells in tear-producing glands than young mice
The catchGene activity was a proxy for immune function, not a direct functional measurement