Impaired renal function
2 papers3 findings
- Humans2
Associations
3Urinary nickel
upin humans1OR 1.26
1 study
Urinary nickel
upin humans1OR 1.26
Urinary nickel is associated with impaired renal function in humans (OR 1.26, 95% CI 1.05–1.51).
“the comparison with the Q1 revealed that the Q4 group of urinary nickel had a 26% increased risk of impaired renal function (OR=1.26, 95%CI: 1.05-1.51).”
HumansQ4 versus Q1 of urinary nickel; adjusted for covariatesboth; 54.73% femalesn = 5,045
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi10 Jun 2026
Mortality
upin humans1HR 1.5
1 study
Mortality
upin humans1HR 1.5
Impaired renal function raises the risk of mortality in humans (HR 1.50, 95% CI 1.34–1.68).
“eGFR <45 mL/min/1.73 m 2 (compared to ≥45) were associated with an increased risk of mortality (HR (95% CI): 1.12(1.04-1.20) and 1.50(1.34-1.68), respectively).”
Humans18.1 yearsn = 6,573
AHA Scientific Sessions 2025 abstract3 Nov 2025
Atrial cardiopathy
upin humans1OR 1.44
1 study
Atrial cardiopathy
upin humans1OR 1.44
Impaired renal function raises the risk of atrial cardiopathy in humans (OR 1.44, 95% CI 1.16–1.78).
“eGFR <45 (compared to ≥45) mL/min/1.73 m 2 was associated with increased risk of atrial cardiopathy (OR (95% CI): 1.44(1.16–1.78)).”
Humansn = 6,573
AHA Scientific Sessions 2025 abstract3 Nov 2025
Trial sponsors
Company1 trialPhase 417 people
1 trialPhase 439 people
1 trialPhase 327 people