Brain injury
Disease1 paper
- Humans1
Trial sponsors
Company1 trialPhase 31,195 people
1 trialPhase 4144 people
1 trialPhase 456 people
1 trialPhase 446 people
1 trialPhase 420 people
University of North Carolina, Chapel Hill
1 trialPhase 48 people
1 trialPhase 218 people
Medical University of South Carolina
1 trialPhase 1/246 people
Funding
National Institute of Neurological Disorders and StrokeUS$7.1mNational Institute on AgingUS$6.4mVeterans Affairs25 grants since 2017
Novel treatments of chronic pain due to repetitive mild traumatic brain injury
Biological Mechanisms Underlying Progressive Decline Following Geriatric Traumatic Brain Injury
National Institute of Neurological Disorders and StrokeLovelace Biomedical Research InstituteUS$690.7k2026–2031
Traumatic Brain Injury, Social Relationships, and Risk of Dementia
National Institute on AgingUniversity of PennsylvaniaUS$76.8k2025–2027
National Institute on AgingUT Southwestern Medical CenterUS$1.1m2026–2031
National Institute of Neurological Disorders and StrokeUniversity of MinnesotaUS$1m2023–2028
National Institute of Neurological Disorders and StrokeUniversity of PennsylvaniaUS$658.7k2026–2031
National Institute of Neurological Disorders and StrokeUniversity of Vermont & St Agric CollegeUS$249k2023–2027
The Young Gut Microbiome: A Fountain of Youth for Brain Injury in the Aged?
National Institute of Neurological Disorders and StrokeNorthwestern UniversityUS$712.5k2023–2028
National Institute of Neurological Disorders and StrokeMassachusetts General HospitalUS$1.9m2026–2029
Latest
77Mild brain injury burden linked to aging brain pathways
A cross-sectional study of 710 US Veterans aged 19–80 linked higher cumulative injury burden to more pronounced age-related differences in brain…A cross-sectional study of 710 US Veterans aged 19–80 linked higher cumulative injury burden to more pronounced age-related differences in brain pathway condition.
Delirium after head injury is linked to higher dementia risk
In a matched cohort, patients with delirium within 14 days of brain trauma had higher two-year risk of dementia (hazard ratio 2.47).In a matched cohort, patients with delirium within 14 days of brain trauma had higher two-year risk of dementia (hazard ratio 2.47).
Brain small vessel disease links to stroke and mortality risk
Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.
Fenofibrate improves cognition in chronic brain injury trial
In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved…In a randomized trial of 40 older adults with chronic traumatic brain injury, fenofibrate lowered plasma neurofilament light chain levels and improved cognitive function.