Dementia incidence

Disease

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Planetary health diet

downin humans1

1 study
  1. Planetary health diet is associated with dementia incidence in humans.

    “Epidemiological evidence from large cohorts links higher PHD adherence to lower MASLD prevalence and severity, slower cognitive decline, reduced dementia incidence”

    Reviewhigher dietary adherence

    Planetary Health Diet and the Gut-Liver-Brain Axis: Implications for MASLD and Cognitive Aging

    Nutrients5 Oct 2026

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Research Square

Some erectile dysfunction drugs linked to fewer dementia diagnoses

Among male veterans with erectile dysfunction, drug use was associated with fewer Alzheimer dementia diagnoses than non-use, with an odds ratio of 0.91.Among male veterans with erectile dysfunction, drug use was associated with fewer Alzheimer dementia diagnoses than non-use, with an odds ratio of 0.91.

Preprint: cohort study of 878,240 male Veterans with erectile dysfunction, against PDE5 inhibitor nonusersErectile dysfunction

Limit: Advanced neurodegenerative disease may reduce treatment uptake, making users appear protected

Nutrients

Diet’s link to dementia differed by gene variant in older adults

In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).

Cohort study of 745 older adultsAll-cause dementia

Limit: Diet was assessed using food-frequency questionnaires, which are subject to measurement error

American Journal of Epidemiology

Dementia risk estimates varied with classification method

Estimated dementia rates ranged from 26.5 to 62.8 cases per 1,000 person-years across four classification methods applied to adults aged 70 and older.Estimated dementia rates ranged from 26.5 to 62.8 cases per 1,000 person-years across four classification methods applied to adults aged 70 and older.

Cohort study of participants age 70+, against participants assessed with the Hudomiet methodDementia

Limit: Without gold-standard longitudinal diagnoses, the study cannot establish which algorithm's estimates are accurate

JAMA Neurology

Dementia developed more often in low- and middle-income countries

After standardising for age and sex, rates were 13.6 new cases per 1,000 person-years in low- and middle-income countries, versus 8.3 in high-income countries.After standardising for age and sex, rates were 13.6 new cases per 1,000 person-years in low- and middle-income countries, versus 8.3 in high-income countries.

Study of 38,418 peopleAll-cause dementia
Alzheimer's & Dementia

Higher residential greenspace links to lower dementia risk

Higher greenspace within 100 meters was linked to lower dementia incidence, with a hazard ratio of 0.79 overall and 0.69 in women compared to 0.93 in men.Higher greenspace within 100 meters was linked to lower dementia incidence, with a hazard ratio of 0.79 overall and 0.69 in women compared to 0.93 in men.

Cohort study of 2,993 peopleDementia