3 papers1 finding
Frailty
upin humans1
Cognitive deficits are associated with frailty in humans.
“elder elderly, female and with a cognitive deficit scored higher on the frailty diagnosis.”
Humansn = 137
Revista latino-americana de enfermagem1 Jan 2009
University of California Los Angeles
1 trialPhase 451 people
Azienda Ospedaliero-Universitaria di Parma
1 trialPhase 340 people
1 trialPhase 130 people
National Institute on AgingUS$6.3mNational Institute of Neurological Disorders and StrokeUS$2.7mNational Institute of Mental HealthUS$202.5k
Role of kynurenic acid in higher cognitive deficits: Mechanism and treatment strategies
National Institute on AgingYale UniversityUS$717.8k2023–2028
National Institute on AgingPennsylvania State Univ Hershey Med CtrUS$236k2026–2028
National Institute on AgingUniversity of California at DavisUS$714.5k2022–2028
National Institute of Neurological Disorders and StrokeMassachusetts General HospitalUS$503k2022–2027
Neuroplasticity and the emergence of motor and cognitive deficits in prodromal synucleinopathy
National Institute of Neurological Disorders and StrokeUniversity of MinnesotaUS$787.2k2022–2028
Role of kynurenic acid in higher cognitive deficits: Mechanism and treatment strategies
National Institute on AgingYale UniversityUS$2.2m2023–2026
National Institute on AgingUniversity of California at DavisUS$317.4k2022–2025
National Institute of Mental HealthUniversity of California, San DiegoUS$202.5k2019–2025
National Institute on AgingBiosensicsUS$1.2m2020–2026
Low versus high social satisfaction was linked to an attention-score gap comparable to that associated with being approximately 5.8 years older.Low versus high social satisfaction was linked to an attention-score gap comparable to that associated with being approximately 5.8 years older.
AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.
In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive aging at age 60.In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive aging at age 60.
A meta-analysis found moderate cognitive deficits (g = -0.48) in chronic pain, and UK Biobank participants with four or more pain sites showed advanced cognitive age.A meta-analysis found moderate cognitive deficits (g = -0.48) in chronic pain, and UK Biobank participants with four or more pain sites showed advanced cognitive age.