Aging diseases

Disease

1 paper1 finding

Associations

1

Inflammation

upin reviews1

1 study
  1. Inflammation is associated with aging diseases.

    “inflamm-aging is intensively associated with many aging diseases, such as Alzheimer's disease, atherosclerosis, heart disease, type II diabetes, and cancer.”

    Review

    An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment

    Journal of immunology research14 Jul 2016

More on Inflammation

Funding

3 grants since 2016

Japan Society for the Promotion of ScienceJP¥23.4mVetenskapsrådetSEK 4m

Latest

Nov 2025: 4Dec 2025: 7Jan 2026: 2Feb 2026: 3Mar 2026: 4Apr 2026: 1May 2026: 2Jun 2026: 3Jul 2026: 5Aug 2026: 4Sep 2026: 10Oct 2026: 449 in 12 months
bioRxiv

Progeria disrupts cells in the intestinal lining in mice

Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.

Preprint: experiments in miceLMNA
Science Advances

Support cells worsened disease features in lab-grown human vessels

Experiments with three-layer vessels built from human cells found that support cells increased several vascular disease features in a model of Hutchinson-Gilford progeria…Experiments with three-layer vessels built from human cells found that support cells increased several vascular disease features in a model of Hutchinson-Gilford progeria syndrome.

Experiments in human cellsMechanisms
Current Medical Research and Opinion

Generalised myasthenia gravis linked to higher death risk

Medicare beneficiaries with the disease had 8% higher mortality risk at 12 months than those without myasthenia gravis.Medicare beneficiaries with the disease had 8% higher mortality risk at 12 months than those without myasthenia gravis.

Cohort study of 373,210 peoplePopulations
Genes

Blood methylation clocks capture two distinct biological domains of aging

Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle…Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.

Cohort study in peopleBiomarkers