Age-related osteoarthritis

Disease

1 paper1 finding

  • Animals1

Interventions

1

NAD@NPs@HM

downin mice1

1 study
  1. NAD@NPs@HM protects against age-related osteoarthritis in mice.

    “Intra-articular injection of NAD@NPs@HM in aged mice reduced the mechanisms associated with AROA.”

    Animals

    Nicotinamide Adenine Dinucleotide-Loaded Lubricated Hydrogel Microspheres with a Three-Pronged Approach Alleviate Age-Related Osteoarthritis

    ACS nano2 May 2025

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Journal of Orthopaedic Translation

Low-intensity exercise eases age-related osteoarthritis in mice

In aged mice and cultured chondrocytes, swimming and a targeted PGC-1α-activating nanoparticle suppressed senescence and altered glycolysis to protect joints.In aged mice and cultured chondrocytes, swimming and a targeted PGC-1α-activating nanoparticle suppressed senescence and altered glycolysis to protect joints.

Experiments in miceExercise