7 papers2 findings
Biological-age acceleration
upin humans1
Biological-age acceleration raises the risk of age-related eye diseases in humans.
“Participants with higher BAA were more likely to experience AREDs at baseline and had an increased risk of incident AREDs during follow-up.”
Humans
Investigative ophthalmology & visual science3 Nov 2025
SIRT1
upin humans1
SIRT1 raises the risk of age-related eye diseases in humans.
“its expression or activity decreases can accelerate cell senescence and promote the occurrence and development of AREDs”
Reviewdecreased expression or activity
SIRT1 as a potential target for age-related eye diseases: mechanisms and therapeutic strategies
Human cell7 Sep 2025
National Eye InstituteUS$115.2k
In 1,013 adults, scores for distinguishing future cardiovascular events were 0.665 for the eye-based model versus 0.647 for a standard calculator, without a significant…In 1,013 adults, scores for distinguishing future cardiovascular events were 0.665 for the eye-based model versus 0.647 for a standard calculator, without a significant difference.
The retinal age gap correlates with mortality, disease risks, and sex-specific genetic pathways in more than 71,000 UK Biobank participants.The retinal age gap correlates with mortality, disease risks, and sex-specific genetic pathways in more than 71,000 UK Biobank participants.