Ventricular function

Papers on ventricular function

170 papers26 new in 30 days

Monday, November 9

AHA Scientific Sessions 2026 AbstractNov 9

Pleiotropic Effects of Dapagliflozin on Angina Pectoris: A Retrospective Analysis

Study in peopleInterventions

Sunday, November 8

Nature MedicineNov 8

Semaglutide improved heart filling in obesity-related heart failure

Semaglutide improved how much the heart’s upper left chamber stretched by 5.7 percentage points versus placebo over 52 weeks in a 49-person trial substudy.Semaglutide improved how much the heart’s upper left chamber stretched by 5.7 percentage points versus placebo over 52 weeks in a 49-person trial substudy.

Heart sections compare an expanded upper chamber in dark blue-green with a smaller gray heart showing narrower chambers and thicker muscle.

Randomized trial · 49 peopleSemaglutide

Monday, November 2

medRxivNov 2

Twenty-Hour Hypothermic Oxygenated Perfusion Preserves Myocardial Viability and Bioenergetics with No Primary Graft Dysfunction After Porcine Heart Transplantation

Preprint: experiments in pigsInterventions

Friday, October 30

Frontiers in Cardiovascular MedicineOct 30

Association of GLP-1 Receptor Agonist Use With Echocardiographic Pulmonary Pressure and Right Ventricular Function in Type 2 Diabetes: A Retrospective Cohort Study

Accepted, not yet published: cohort study of 1,200 peoplePulmonary hypertension

American Journal of Cardiovascular DrugsOct 30

Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial

Figure from American Journal of Cardiovascular Drugs

Randomized trial in 120 peopleNicotinamide adenine dinucleotide

Thursday, October 29

Frontiers in TransplantationOct 29

Improved preservation of hearts from old donors during static cold storage by the senomorphic agent ruxolitinib

Figure from Frontiers in Transplantation

Experiments in animalsStatic cold storage

Frontiers in Cardiovascular MedicineOct 29

Association between chronic sodium-glucose cotransporter 2 inhibitors use and right ventricular function in hemodynamically stable patients with acute pulmonary embolism

Figure from Frontiers in Cardiovascular Medicine

Cohort study of 90 peopleLung

Monday, October 26

ESC Congress 2026 AbstractOct 26

Beta-blockers tied to fewer deaths in selected heart attack patients

Major heart complications occurred in 20.9% of patients taking beta-blockers compared with 25.4% without them over a median follow-up of 998 days.Major heart complications occurred in 20.9% of patients taking beta-blockers compared with 25.4% without them over a median follow-up of 998 days.

A cutaway heart beneath a molecule and clusters of smaller hearts, with more broken shapes in the gray cluster than the dark blue-green cluster.

Cohort · 2,566 peopleBeta-blockers

ESC Congress 2026 AbstractOct 26

Prophylactic dapagliflozin attenuates pulmonary vascular remodelling, preserves right ventricular function, and maintains exercise capacity in a monocrotaline-induced pulmonary hypertension rat model

Experiments in 24 ratsDapagliflozin

ESC Congress 2026 AbstractOct 26

Cardiac remodelling detected by imaging and circulating biomarkers in the general population associated with elevated blood pressure and hypertension

Cross-sectional study of 9,589 peopleElevated blood pressure

ESC Congress 2026 AbstractOct 26

Liraglutide reduces myocardial metalloproteinase 2 activity without attenuating doxorubicin-induced cardiac dysfunction in rats

Experiments in 60 ratsLiraglutide

ESC Congress 2026 AbstractOct 26

Clinical profile and determinants of NECPAL positivity in advanced cardiorenal syndrome: a prospective multicentre study

Cohort study of 124 peopleBiomarkers

ESC Congress 2026 AbstractOct 26

Exercise training protects against myocardial infarction by regulating B cell infiltration and function

Experiments in miceExercise training

ESC Congress 2026 AbstractOct 26

Sustained delivery of running-derived exosomes improves heart function after myocardial infarction

Figure from ESC Congress 2026 Abstract

Experiments in miceInterventions

ESC Congress 2026 AbstractOct 26

Sex-based differences in baseline characteristics, periprocedural outcomes and long-term survival following transcatheter aortic valve implantation

Cohort study of 4,331 peoplePopulations

ESC Congress 2026 AbstractOct 26

Targeting cardiac remodeling and sirtuin gene expression in type 1 diabetes mellitus: role of dapagliflozin

Experiments in ratsDapagliflozin

ESC Congress 2026 AbstractOct 26

Myocardial deformation assessed by machine learning is associated with heart failure, atrial fibrillation, and mortality in the elderly

Cohort study of 1,363 peopleAtrial fibrillation

ESC Congress 2026 AbstractOct 26

Ethnic differences in new-onset atrial fibrillation using multidimensional data

Cohort study of 502,412 peopleNew-onset atrial fibrillation

ESC Congress 2026 AbstractOct 26

Sex-specific echocardiographic predictors of atrial fibrillation in the general population

Cohort study of 4,070 peopleIncident atrial fibrillation

ESC Congress 2026 AbstractOct 26

Early in-hospital initiation of dapagliflozin versus empagliflozin in acute heart failure: impact on in-hospital survival and safety

Cohort study of 1,546 peopleDapagliflozin

ESC Congress 2026 AbstractOct 26

Role of SGLT2I in improving right ventricular systolic function in patients with HFpEF

Non-randomized trial in 100 peopleSGLT2 inhibitors

ESC Congress 2026 AbstractOct 26

Impact of right atrial remodeling on mortality after transcatheter aortic valve implantation

Cohort study of 185 peopleBiomarkers

Sunday, October 25

European Journal of Applied PhysiologyOct 25

The ascending aorta and vascular profile in recreational masters runners: a cross-sectional study

Figure from European Journal of Applied Physiology

Cross-sectional study of 42 peoplePopulations

Saturday, October 24

Pulmonary Pharmacology & TherapeuticsOct 24

Cellular Senescence and Vascular Ageing in Pulmonary Hypertension: Molecular Mechanisms, Therapeutic Strategies, and Translational Endpoints

Figure from Pulmonary Pharmacology & Therapeutics

ReviewCellular senescence

Friday, October 23

JACC Heart FailureOct 23

Cardiac Structure and Function in Women After Preeclampsia: A Systematic Review and Meta-Analysis

Figure from JACC Heart Failure

Meta-analysis of observational studiesPreeclampsia

Sunday, October 18

CureusOct 18

Beyond Prognosis: A Systematic Review of the Neutrophil-to-Lymphocyte Ratio as a Modifiable Cardiovascular Biomarker

PRISMA flow diagram of the study identification, screening, eligibility assessment, and inclusion process.

Systematic review of randomized trialsCardiovascular disease

Wednesday, October 7

Aging CellOct 7

Exercise or drugs improved heart function in aging mice

A nine-month randomized experiment in 12-month-old mice compared exercise (11 mice), two drugs (15), both (16) and natural aging (12); the interventions improved heart…A nine-month randomized experiment in 12-month-old mice compared exercise (11 mice), two drugs (15), both (16) and natural aging (12); the interventions improved heart performance.

Mice given aerobic exercise, senolytics, or both combined for 9‐months display superior myocardial function to naturally aged mice.

Experiments in miceAerobic exercise

Thursday, September 10

Scandinavian Journal of Medicine & Science in SportsSep 10

Right Heart Cardiac Magnetic Resonance Profiles and Cardiopulmonary Reserve in Older Adults Undergoing Long-Term Multicomponent Exercise: A 2-Year Longitudinal Study

Research flow chart.

Non-randomized trial in 155 peopleExercise

Tuesday, September 1

ESC Heart FailureSep 1

Dapagliflozin effects on right ventricular function, pulmonary pressure and coupling: a propensity score analysis from the RIVED-HF

Figure from ESC Heart Failure

Cohort study of 142 peopleDapagliflozin

GeroScienceSep 1

Sodium-glucose cotransporter 2 inhibitors are associated with reduced circulating activin A and modulation of BMP/activin signaling in ischemic cardiomyopathy with high echocardiographic probability of pulmonary hypertension

Figure from GeroScience

Non-randomized trial in 74 peopleSGLT2 inhibitors