Ubiquitinated protein aggregates
2 papers1 finding
- Model organisms2
Interventions
1Sesamin
downin flies1
1 study
Sesamin
downin flies1
Sesamin decreases ubiquitinated protein aggregates in flies.
“Sesamin, which has antioxidant effects on cultured cells and Drosophila neurons, suppresses this muscle-aging phenotype.”
Model organismsagingmuscle
Preprints.org8 May 2025Preprint
Latest
Communications Biology
UBE2V1 governs aging induced protein aggregation and developmental defects in oocytes and embryos
Experiments in miceMechanisms
Preprints.org
Sesamin Suppresses Aging-Associated Impairment of Protein Homeostasis in Adult Drosophila Muscles by Stimulating Autophagy
Preprint: experiments in fliesMuscle
Genetics
Autophagy impairment and lifespan reduction caused by Atg1 RNAi or Atg18 RNAi expression in adult fruit flies (Drosophila melanogaster)
Experiments in model organismsMechanisms
bioRxiv
Knockdown of Atg1 or Atg18 in adult adipocytes impairs lipophagy and reduces lifespan of fruit flies ( Drosophila melanogaster )
Preprint: experiments in fliesMechanisms
European Review for Medical and Pharmacological Sciences
Metformin suppresses progression of muscle aging via activation of the AMP kinase-mediated pathways in Drosophila adults
Experiments in model organismsInterventions