1 paper1 finding
Shingles vaccine
downin humans1
Shingles vaccine decreases transcriptomic aging in humans (b = -0.19, p < .0001).
“transcriptomic aging (b = -0.19, p < .0001)”
Humansn = 3,884
The journals of gerontology. Series A, Biological sciences and medical sciences20 Jan 2026
Human neural, cardiac, and tonsil organoids exposed to 24 hours of simulated microgravity showed tissue-specific changes, including higher transcriptomic-age estimates in…Human neural, cardiac, and tonsil organoids exposed to 24 hours of simulated microgravity showed tissue-specific changes, including higher transcriptomic-age estimates in brain and heart models.
A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.
Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.