Transcriptomic age acceleration
2 papers study it4 more mention it1 finding
- Humans2
Upstream
1Tuberculosis
upin humans1
1 study
Tuberculosis
upin humans1
Tuberculosis increases transcriptomic age acceleration in humans (14.38 years (95% CI: 10.23-18.53)).
“Humans with TB demonstrate 12.7 years (95% CI: 7.5, 21.9) and 14.38 years (95% CI: 10.23-18.53) of cellular aging as measured by epigenetic and gene expression based cellular clocks, respectively.”
HumansTB patients compared to healthy controls
Aging
Latest
2 papers in 12 monthsPsychological Medicine
Peripheral transcriptomic aging acceleration in major depressive disorder: the mediating role of insular cortex alterations
Case-control study of 141 peopleMajor depressive disorder
Clinical Psychopharmacology and Neuroscience
Cellular Senescence of Patient-derived Fibroblasts Reveals the Mid-old Stage as a Critical Window for Transcriptomic Signatures Linked to Alzheimer's Disease Biomarkers and Classification
Study in peopleAlzheimer's disease
bioRxiv
Whole blood transcriptional signatures of age and survival identified in Long Life Family and Integrative Longevity Omics Studies
Preprint: cohort study of 2,167 peopleMechanisms
bioRxiv
CpGeneAge: multi-omics aging clocks associated with Nf-κB signaling pathway in aging
Preprint: computational studyBiomarkers
Aging Cell
Transcriptomics age acceleration in prolonged treated HIV infection
Cohort study of 178 peopleHIV infection