Jornal Brasileiro de Pneumologia
Expression of angiotensin-converting enzyme 2, transmembrane serine protease 2, and sirtuin 1 proteins in lungs of different age groups
Cross-sectional study of 43 peopleSirtuin signaling
Papers on TMPRSS2
22 papers
Wednesday, June 17
Tuesday, March 17
Tuesday, March 10
Free Radical Biology & Medicine
The role of metabolic stress, xanthine oxidase, NOX2, and redox-related signalling in regulating ACE2 protein expression in exercising human skeletal muscle
Non-randomized trial in 11 peopleMuscle
Thursday, February 19
Thursday, August 14
International Journal of Molecular Sciences
Impact of Obesity and Ageing on the Expression of Key Mediators of SARS-CoV-2 Infection in Human Adipose Tissue
Cross-sectional study in peopleMechanisms
Wednesday, June 25
Monday, January 27
BioFactors
Involvement of metformin and aging in salivary expression of ACE2 and TMPRSS2
Experiments in miceMetformin
Tuesday, March 26
The Journal of Clinical Investigation
Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
Study in peopleDNA damage response
Saturday, August 26
Tuesday, January 17
bioRxiv
The emergence of goblet inflammatory or ITGB6 hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis
Preprint: experiments in human cellsMechanisms
Thursday, November 25
Journal of Virology
Age-Related Susceptibility of Ferrets to SARS-CoV-2 Infection
Experiments in animalsMechanisms
Monday, November 15
Journal of Molecular and Cellular Cardiology
Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility
Experiments in miceMechanisms
Sunday, August 22
Genomics
Co-expression of the SARS-CoV-2 entry molecules ACE2 and TMPRSS2 in human ovaries: Identification of cell types and trends with age
Cross-sectional study in peopleReproductive system
Saturday, August 7
Biomedicines
Expression of SARS-CoV-2 Entry Factors in Human Alveolar Type II Cells in Aging and Emphysema
Cross-sectional study in peopleMechanisms
Tuesday, June 8
Wednesday, December 30
Scientific Reports
Neonatal hyperoxia enhances age-dependent expression of SARS-CoV-2 receptors in mice
Experiments in animalsMechanisms
Tuesday, October 6
Frontiers in Pharmacology
Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis
Cross-sectional study in peopleTelomerase and telomere maintenance
Friday, July 24
Research Square
Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis
Preprint: cross-sectional study in peopleTelomerase and telomere maintenance
Saturday, June 27
Friday, April 24
Antioxidants & Redox Signaling
Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19?
Computational studyMechanisms
Monday, April 20
Sunday, October 30
Frontiers in Genetics
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases
Study in peopleMechanisms