There are 5 papers on TMPRSS2 in aging research: 1 trial and 2 observational studies in people, 2 in animals.
5 papers study it17 more mention it1 finding
- Human trial1
- Humans2
- Animals2
Interventions
1Exercise
upin humans1
1 study
Exercise
upin humans1
Exercise increases TMPRSS2 in humans (at exhaustion and with post-exercise ischemia).
“Transmembrane protease, serine 2 (TMPRSS2) protein expression increased at exhaustion and rose further with ischaemia.”
Human trialat exhaustion and with post-exercise ischemiavastus lateralismalesn = 11
Free radical biology & medicine
Latest
4 papers in 12 monthsFree Radical Biology & Medicine
The role of metabolic stress, xanthine oxidase, NOX2, and redox-related signalling in regulating ACE2 protein expression in exercising human skeletal muscle
Non-randomized trial in 11 peopleMuscle
International Journal of Molecular Sciences
Impact of Obesity and Ageing on the Expression of Key Mediators of SARS-CoV-2 Infection in Human Adipose Tissue
Cross-sectional study in peopleMechanisms
BioFactors
Involvement of metformin and aging in salivary expression of ACE2 and TMPRSS2
Experiments in miceMetformin
Journal of Molecular and Cellular Cardiology
Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility
Experiments in miceMechanisms
Biomedicines
Expression of SARS-CoV-2 Entry Factors in Human Alveolar Type II Cells in Aging and Emphysema
Cross-sectional study in peopleMechanisms
Jornal Brasileiro de Pneumologia
Expression of angiotensin-converting enzyme 2, transmembrane serine protease 2, and sirtuin 1 proteins in lungs of different age groups
Cross-sectional study of 43 peopleSirtuin signaling
The Journal of Clinical Investigation
Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
Study in peopleDNA damage response