Th1 cells

Biomarker

3 papers3 findings

  • Human trial1
  • Humans2

Effects

1

Immune response

upin mice1

1 study
  1. Th1 cells increase immune response in mice.

    “which augmented humoral immunity in aged mice”

    Animals

    Pre-Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS-CoV-2 Inactivated Vaccines

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)16 Nov 2025

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Associations

2

P53+ granulocytes

upin humans1

1 study
  1. P53+ granulocytes are associated with Th1 cells in humans (p < 0.05).

    “Spearman analyses supported these trends and further revealed positive associations between p16+ monocytes and Th17 cells and between p53+ granulocytes and Th1 cells (p < 0.05).”

    Humansin early pregnancyperipheral bloodfemalesn = 52

    Disrupted immune senescence in early pregnancy is associated with recurrent pregnancy loss

    Frontiers in immunology4 Feb 2026

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Antigen-specific antibody titers

upin humans1

1 study
  1. Th1 cells predict antigen-specific antibody titers in humans (r = 0.423, p = 0.001).

    “exhibit a modest positive correlation with post-vaccination antibody titers (r = 0.423, p = 0.001)”

    Humans

    Pre-Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS-CoV-2 Inactivated Vaccines

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)16 Nov 2025

More on Antigen-specific antibody titers

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