Structural MRI
Biomarker2 papers
Latest
71Gut metabolites linked to preserved brain thickness in older adults
In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults…In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults eating walnuts.
Brain scan findings linked to symptom relief in memory trial
In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom…In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom reductions.
Brain thinning detected before dementia in people under 65
An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.
Brain age estimates were higher across six disorders
The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.
Pipeline prepares brain scans for aging and Alzheimer’s research
Processing more than 2,800 imaging sessions yielded 2,086 quality-checked sessions from 935 participants for research on aging and Alzheimer’s…Processing more than 2,800 imaging sessions yielded 2,086 quality-checked sessions from 935 participants for research on aging and Alzheimer’s disease.
Brainstem volume links to better memory in midlife
In 198 adults aged 40 to 65, larger brainstem volume tied to better memory, with the strongest link seen in participants with elevated arterial…In 198 adults aged 40 to 65, larger brainstem volume tied to better memory, with the strongest link seen in participants with elevated arterial stiffness.
Multimodal PET and MRI predict dementia with Lewy bodies
Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution…Combined occipito-parietal cortex pathology and striatal dopamine loss predicted conversion to dementia with Lewy bodies with a sub-distribution hazard ratio of 38.68.
AI model predicts Alzheimer's conversion across cohorts
In 101 people with mild cognitive impairment, the model predicted conversion with an AUC of 0.72 and mirrored rates of brain atrophy and cognitive…In 101 people with mild cognitive impairment, the model predicted conversion with an AUC of 0.72 and mirrored rates of brain atrophy and cognitive decline.