Aβ42/Aβ40

Biomarker4 papers1 finding

Humans3

Associations

DunedinPACE

downin humans1

1 study

DunedinPACE is associated with Aβ42/Aβ40 in humans (β=-0.11, p=0.024).
“DunedinPACE was negatively associated with Aβ42/Aβ40 (rho=‐0.099, p = 0.016, Figure 2C), indicating greater amyloid burden with accelerated aging, and this association was significant when adjusting for chronological age, sex, race, APOE‐ε4 status”
Humansadjusted for age, sex, race, APOE-ε4, and clinical statusplasman = 618
Epigenetic age acceleration is faster in Black adults and is associated with plasma amyloid · AAIC 2025 abstract · 25 Dec 2025

DunedinPACE →

Latest

Frontiers in NeurologyReviewYesterday

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Obstructive sleep apnea

Experimental NeurologyAnimals2 Oct

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Biomarkers

Frontiers in Aging NeuroscienceHumans30 Sep

Stronger rest-activity rhythms link to better executive function

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Populations

GeroScienceReview19 Sep